本論文研究為二氧化鈦光電奈米線穩健組裝及其應用於肺癌標記物感測器之開發，內容主要可分成三個部份，第一部分技術為可程式化介電泳穩健組裝系統，利用此系統可以自動判定組裝於微電極間隙上之奈米線阻抗；第二部分技術為介電泳過濾系統，利用此系統可以篩選掉非奈米線之雜質，結合第一部分技術可精密穩健地組裝出10排奈米線陣列；第三部分技術為將二氧化鈦奈米線感測器應用於檢測肺癌標記物之一(2-丙基-1-戊醇)，利用3-氨丙基三甲氧基進行化學修飾而提高感測器對此肺癌標記物之靈敏性、專一性以及選擇性。
在可程式化介電泳穩健組裝系統中，本研究利用LabVIEW軟體設計一個可程式化組裝系統達成同時監控結果與進行組裝，透過此設計提高了奈米線組裝的穩健度，此外利用電極的形狀來控制組裝的數量達到穩健組裝的目標。從ANSYS模擬結果可以得知90度尖形電極所形成的電場強度最集中且最強。然而在介電泳過濾系統中，圓形指叉狀電極的過濾效率最高，在流速為1 μL/min進行過濾之過濾效率為93.3 %。由所開發之技術來進行組裝，以一組10排奈米線之組裝來看，成功率由0 %提高到90 %。
本論文針對二氧化鈦奈米線感測器反應時間與閘極偏壓、紫外光強度之關係進行探討，並且應用於肺癌標記物之一(2-丙基-1-戊醇)之檢測。由實驗結果得知當施加偏壓達到其崩潰電壓3.4 V，其反應時間為62.5毫秒；當紫外光強度為6 mW/cm2時，其光電轉換效率為56.38 %。肺癌標記物感測實驗方面，測試了甲醇、乙醇、丙酮及2-丙基-1-戊醇不同濃度之氣體，在200 ppb濃度之感測專一性提升7.66倍、感測靈敏度提升1.72倍、選擇性提升213.68倍，其偵測極限為0.02 ppb。本論文研究所開發之肺癌標記物感測器未來有潛力應用於其他呼吸疾病檢測以及環境安全檢測等多方應用。

摘要
Abstract
致謝
目錄
圖目錄
表目錄
第一章 緒論
1.1 研究背景
1.2 奈米材料自組裝技術
1.2.1 化學氣相沉積自組裝
1.2.2 磁力場自組裝
1.2.3 表面官能基自組裝
1.2.4 電場自組裝
1.3 研究動機
1.4 研究目的與方法
1.5 論文架構
第二章 光電半導體奈米線
2.1 光電半導體簡介
2.2 光電半導體能帶
2.3 光電半導體蕭基能障
2.4 光電半導體接面崩潰
2.5 光電半導體光催化反應
第三章 穩健光電半導體奈米線組裝之技術與平台
3.1 光電半導體二氧化鈦奈米線電紡絲製程
3.2 穩健組裝技術與平台建構
3.2.1 奈米線穩健組裝技術
3.2.1.1 介電質極化理論
3.2.1.2 介電泳原理
3.2.1.3 介電泳數學模型
3.2.2 穩健組裝平台架構
3.2.2.1 LabVIEW程式設計
3.2.2.2 LabVIEW人機介面
3.2.2.3 LabVIEW組裝平台
3.3 有限元素法介電泳組裝模擬與分析
3.3.1 電極幾何形狀模擬與分析
3.3.2 電極Z方向電場模擬與分析
3.3.3 二氧化鈦溶液濃度模擬與分析
3.4 穩健組裝平台應用於奈米材料之組裝
3.4.1 穩健組裝平台應用於二氧化鈦奈米線之組裝
3.4.2 穩健組裝與不同參數之探討
3.4.2.1 穩健組裝與不同流速之關係
3.4.2.2 穩健組裝與不同濃度之關係
3.4.3 穩健組裝平台之過濾系統架設
3.4.3.1 二氧化鈦溶液之材料種類
3.4.3.2 過濾電極與過濾效率之關係
3.4.3.3 過濾系統與流速之關係
3.4.3.4 過濾系統應用於尖形電極以及陣列組裝
3.5 結論
第四章 二氧化鈦奈米線感測器之電性量測
4.1 單根二氧化鈦奈米線電性量測
4.2 二氧化鈦奈米線感測器阻抗量測
4.3 紫外光強度與二氧化鈦奈米線感測器阻抗值之關係
4.4 閘極偏壓與二氧化鈦奈米線感測器阻抗值之關係
4.5 結論
第五章 二氧化鈦奈米線感測器應用於肺癌標記物檢測
5.1 肺癌感測器設計與規劃
5.2 肺癌標記物與有機氣體感測結果
5.3 肺癌標記物與有機氣體化學修飾感測結果
5.4 肺癌標記物與有機氣體選擇性感測結果
5.5 結論
第六章 結論以及研究成果與研究發表
6.1 總結
6.2 研究成果
6.3 本研究之學術貢獻點
6.4 未來研究建議
附錄
參考資料
發表著作
作者簡介

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