偵測光子輻射所應用之光刺激發光劑量計(OSLD)目前常使用的材料是Al2O3 : C，降低材料成本是許多研究學者致力改進的問題，NaCl是環境中容易獲得和成本低廉的材料，亦具有OSLD的特性。由於OSLD計讀系統目前是landauer 公司製作和生產，其系統規格並無法計讀NaCl，因此本研究使用自製光刺激發光計讀儀系統來度量Al2O3 : C、NaCl兩種材料。NaCl以手動液壓機將其製作成錠狀固體並探討NaCl光子劑量計特性。本研究首先使用Al2O3 : C (nanoDot)驗證自製計讀儀之特性，而後將壓錠後之NaCl材料應用於光子輻射度量，評估NaCl OSLD於光子輻射場的再現性、均勻性和劑量特性。結果顯示，壓錠後NaCl OSLD具有以下特性，其再現性與均勻性控制在±20%的誤差範圍，此外由回火速率可知晶體本身對可見光的敏感度極高，應用此材料必需將其外部封裝嚴密。依據NaCl的消光現象(fading)曝露輻射後之計讀時間應於1天後，光子場中NaCl OSLD最低可測劑量為0.3 mGy，本研究於1 Gy以下建立其線性劑量校正曲線。壓錠後之NaCl粒徑大小固定與質量誤差較小，大幅降低計讀時產生的不穩定訊號，雖不具備重複計讀特性，可做為OSLD評估光子劑量。

The optical stimulation luminescence dosimeter (OSLD) for photon radiation detection is usually using Al2O3: C. The cost of dosimeter is also an important consideration for choosing dosimeter in radiation measurement. NaCl is an easy-to-obtain and low-cost material in the environment. NaCl has the characteristics of OSL and is possible to be used as an OSLD. Currently, the Landauer OSLD reader(microStar) is most popular used. However, this reader cannot measure NaCl crystal. Therefore, this study used the homemade reader system developed in the laboratory to measure Al2O3: C and NaCl crystal. NaCl OSLDs were made for solid pellet crystal by a hand-pressed hydraulic machine in this study. Commercial Landauer Al2O3:C dosimeters (nanoDot) were used to verify the characteristics of the homemade reader system. The solid NaCl pellets were applied in photon field to evaluate the reproducibility, homogeneity and dose characteristics of the NaCl OSLD. The results of this study show that its reproducibility and homogeneity of NaCl OSLD have ±20% deviation. In addition, the annealing rate shows that NaCl OSLD is extremely sensitive to visible light. NaCl OSLD must be tightly packaged to avoid visible light. According to the fading of NaCl OSLD, after exposing to radiation the proper reading time should be 1 day later. Lower Limit of Detection (LLD) of NaCl OSLD in the photon radiation field is 0.3 mGy. Linear dose calibration curve was built below 1 Gy. In concluded, the NaCl pellets have fixed particle size and fixed mass, this causes lower uncertainty. Although the reread property is lack for NaCl OSLD, it is still can be used as a cheap and qualified dosimeter.

中文摘要 I
Abstract II
致謝 III
目綠 IV
表目錄 VI
圖目錄 VII
第一章 緒論 1
1.1前言 1
1.2 OSLD原理與材料特性 1
1.2.1 OSLD計讀原理 1
1.2.2重複計讀 5
1.2.3 OSLD校正曲線 7
1.2.4能量依存性 8
1.3文獻回顧 9
1.4 研究目的 12
第二章 材料與方法 13
2.1 氯化鈉(NaCl) 13
2.2 錠狀氯化鈉晶體製作 15
2.3 自製光刺激發光計讀儀與特性測試 16
2.3.1 光刺激發光劑量計計讀流程 17
2.3.2 回火特性 18
2.3.3 自製計讀儀穩定性 19
2.3.4 nanoDot OSLD重複計讀測試 19
2.3.5 背景訊號累積 20
2.3.6 消光(fading) 20
2.3.7 自製計讀儀劑量校正曲線 20
2.4 氯化鈉光子照射實驗設計 21
2.4.1 NaCl回火特性 21
2.4.2 NaCl再現性與均勻性評估 21
2.4.3 NaCl OSLD重複計讀測試 23
2.4.4 背景訊號累積 23
2.4.5 消光(fading) 23
2.4.6 NaCl OSLD校正曲線 23
2.5 最低可測值評估(Lower Limit of Detection, LLD) 24
第三章 結果與討論 27
3.1 OSLD回火後零訊號之標準測定 27
3.2 光刺激發光自製計讀儀特性 35
3.2.1 自製計讀儀之重複計讀特性 35
3.2.2 背景訊號累積(Al2O3 : C) 38
3.2.3 nanoDot OSLD最低可測值評估 39
3.2.4 消光 (fading) 39
3.2.5 nanoDot OSLD校正曲線 40
3.3 NaCl OSLD特性 42
3.3.1 再現性與均勻性評估 42
3.3.2 NaCl OSLD重複計讀測試 45
3.3.3 NaCl背景訊號累積 47
3.3.4 NaCl最低可測值評估 48
3.3.5 NaCl消光(fading) 48
3.3.6 NaCl OSLD校正曲線 49
第四章 結論 51
參考文獻 52

[1] Saylor, General Chemistry Principles, Patterns, and Applications. 2011.
[2] G. F. Knoll, Radiation Detection and Measurement-Wiley 2010.
[3] S. W. S. M. L. Botter-Jensen, A. G. Wintle, Optically Stimulated Luminescence Dosimetry. 2003, pp. 1-355.
[4] M.-H. Wu, "Dosimetric Characteristic Study of Common Salt Applied in Radiation Fields," pp. 1-93,2019
[5] L.-Y. Chen, C.-H. Hsu, and F.-Y. Hsu, "Development and efficacy testing of a new optically stimulated luminescence ring dosimeter and algorithm," Radiation Measurements, vol. 124, pp. 109-115,2019
[6] P. A. Jursinic, "Changes in optically stimulated luminescent dosimeter (OSLD) dosimetric characteristics with accumulated dose," Med Phys, vol. 37, no. 1, pp. 132-40,2010
[7] A. KLUG, "Rosalind Franklin and the Discovery of the Structure of DNA," NATURE, vol. 219, pp. 808-844,1968
[8] J. P. B. L. VERGER, F. GLASSER, and P. OUVRIER-BUFFET, "New Developments in CdTe and CdZnTe Detectors for X and y-Ray Applications," Journal of Electronic Materials,, vol. 26, no. 6, pp. 738-744,1997
[9] S. F. Kry et al., "AAPM TG 191: Clinical use of luminescent dosimeters: TLDs and OSLDs," Med Phys, vol. 47, no. 2, pp. e19-e51,2020
[10] S. B. Scarboro et al., "Characterization of the nanoDot OSLD dosimeter in CT," Med Phys, vol. 42, no. 4, pp. 1797-807,2015
[11] P. A. Jursinic, "Characterization of optically stimulated luminescent dosimeters, OSLDs, for clinical dosimetric measurements," Med Phys, vol. 34, no. 12, pp. 4594-604,2007
[12] E. G. Yukihara and S. W. McKeever, "Optically stimulated luminescence (OSL) dosimetry in medicine," Phys Med Biol, vol. 53, no. 20, pp. R351-79,2008
[13] S. Hashim et al., "Optically stimulated Al2O3:C luminescence dosimeters for teletherapy: Hp(10) performance evaluation," Appl Radiat Isot, vol. 135, pp. 7-11,2018
[14] B. D. K. Le Ngoc Thiem, Trinh Van Giap, Nguyen Huu Quyet, Ho Quang Tuan, Vu Manh Khoi and Chu Vu Long, "Establishing personal dosimetry procedure using optically stimulated luminescence dosimeters in photon and mixed photon - neutron radiation fields," Institute for Nuclear Science and Technology, vol. 49, no. 20, pp. 143-149,2016
[15] L. B.-J. I.M.G. Thompson, S. Deme, F. Pernicka, and J.C. Saez-Vergara, "Radiation Protection106 Technical recommendations on measurements of external environment gamma radiation dose," A report of EURADOS Working Groups 12 "Environment radiation monitoring", pp. 1-202,1999
[16] S. Sao Paulo, Brazil, Methodological developments for application of optically stimulated luminescence (OSL) in medical dosimetry. 2006, pp. 1-198.
[17] L. Benevides, A. Romanyukha, F. Hull, M. Duffy, S. Voss, and M. Moscovitch, "Uncertainties associated with the use of optically stimulated luminescence in personal dosimetry," Radiat Prot Dosimetry, vol. 144, no. 1-4, pp. 165-167,2011
[18] P. Alvarez, S. F. Kry, F. Stingo, and D. Followill, "TLD and OSLD dosimetry systems for remote audits of radiotherapy external beam calibration," Radiat Meas, vol. 106, pp. 412-415,2017
[19] V. K. Asfora et al., "Optically stimulated luminescence of CaF2:Tm," Radiation Measurements, vol. 85, pp. 73-77,2016
[20] R. M. Al-Senan and M. R. Hatab, "Characteristics of an OSLD in the diagnostic energy range," Med Phys, vol. 38, no. 7, pp. 4396-405,2011
[21] T. Yanagida, "Inorganic scintillating materials and scintillation detectors," Proc Jpn Acad Ser B Phys Biol Sci, vol. 94, no. 2, pp. 75-97,2018
[22] T. Yanagida, "Ionizing radiation induced emission: Scintillation and storage-type luminescence," Journal of Luminescence, vol. 169, no. part B, pp. 544-548,2016
[23] W. G. West, K. J. Kearfott, and S. M. Bernal, "The sunlight OSL response of a commercially available alpha-Al2O3:C personnel dosimetry material," Radiation Protection Dosimetry vol. 119, no. 1-4, pp. 344-349,2006
[24] A. J. M. W. A. J. J. Bos, N. J. M. Le Masson, A. V. Sidorenko and C. W. E. van Eijk, "A TL/OSL emission spectrometer extension of the RISØ reader," Radiation Protection Dosimetry, vol. 101, no. 1-4, pp. 111-114,2002
[25] E. Bulur a, L. Bùtter-Jensen a, A.S. Murray b, "Frequency modulated pulsed stimulation in optically stimulated luminescence," Nuclear Instruments and Methods in Physics Research vol. B 179, no. 1, pp. 151-159,2001
[26] T. Yanagida, G. Okada, and N. Kawaguchi, "Ionizing-radiation-induced storage-luminescence for dosimetric applications," Journal of Luminescence, vol. 207, pp. 14-21,2019
[27] R. Majgier, C. L. Raaf, A. Mandowski, and C. Bernhardsson, "OSL properties in various forms of KCl and NaCl samples after exposure to ionizing radiation," Radiat Prot Dosimetry, vol. 184, no. 1, pp. 90-97,2019
[28] S. B. Scarboro and S. F. Kry, "Characterisation of energy response of Al2O3 : C optically stimulated luminescent dosemeters (OSLDs) using cavity theory," Radiat Prot Dosimetry, vol. 153, no. 1, pp. 23-31,2013
[29] C. S. Reft, "The energy dependence and dose response of a commercial optically stimulated luminescent detector for kilovoltage photon, megavoltage photon, and electron, proton, and carbon beams," Med Phys, vol. 36, no. 5, pp. 1690-1699,2009
[30] A. H. Benali, G. M. Ishak-Boushaki, A. M. Nourreddine, M. Allab, and P. Papadimitroulas, "A comparative evaluation of luminescence detectors: RPL-GD-301, TLD-100 and OSL-Al2O3:C, using Monte Carlo simulations," Journal of Instrumentation, vol. 12, no. 07, pp. P07017-P07017,2017
[31] A.S. Murraya, A.G. Wintleb, "Luminescence dating of quartz using an improved singlealiquot regenerative-dose protocol," Radiation Measurements vol. 32, no. 1, pp. 57-73,2000
[32] A. G. M. Wintle, A. S., "A review of quartz optically stimulated luminescence characteristics and their relevance in single-aliquot regeneration dating protocols," Radiation Measurements, vol. 41, no. 4, pp. 369-391,2006
[33] Maseeh uz Zaman, 3 Nosheen Fatima,2,3 Mansoor Naqvi,1 Riffat Parveen,1 Zafar Sajjad1, "Radiation dosimetry : From thermoluminescence dosimeter (TLD) to optically stimulated luminescence dosimetry(OSLD)," Paki stan journal of radiology, vol. 21, no. 3, pp. 107-109,2011
[34] S. W. S. McKeever, "Optically stimulated luminescence: A brief overview," Radiation Measurements, vol. 46, no. 12, pp. 1336-1341,2011
[35] D. Ekendahl, B. Bulánek, and L. Judas, "A low-cost personal dosemeter based on optically stimulated luminescence (OSL) of common household salt (NaCl)," Radiation Measurements, vol. 85, pp. 93-98,2016
[36] M. Christiansson, S. Mattsson, C. Bernhardsson, and C. L. Raaf, "Optimizing a readout protocol for low dose retrospective OSL-dosimetry using household salt," Health Phys, vol. 102, no. 6, pp. 631-636,2012
[37] C. Bernhardsson, M. Christiansson, S. Mattsson, and C. L. Raaf, "Household salt as a retrospective dosemeter using optically stimulated luminescence," Radiat Environ Biophys, vol. 48, no. 1, pp. 21-28,2009
[38] C. Bernhardsson, S. Matskevich, S. Mattsson, and C. Raaf, "Comparative measurements of the external radiation exposure in a 137Cs contaminated village in Belarus based on optically stimulated luminescence in NaCl and thermoluminescence in LiF," Health Phys, vol. 103, no. 6, pp. 740-749,2012
[39] M. Christiansson, C. Bernhardsson, T. Geber-Bergstrand, S. Mattsson, and C. L. Raaf, "Household salt for retrospective dose assessments using OSL: signal integrity and its dependence on containment, sample collection, and signal readout," Radiat Environ Biophys, vol. 53, no. 3, pp. 559-569,2014
[40] M. Christiansson, C. Bernhardsson, S. Mattsson, and C. L. Raaf, "Using an optimised OSL single-aliquot regenerative-dose protocol for low-dose retrospective dosimetry on household salt," Radiat Prot Dosimetry, vol. 144, no. 1-4, pp. 584-587,2011
[41] L. B.-J. a. A. S. M. K. J. Thomsen†, "Household and Workplace Chemicals as Retrospective Luminescence Dosemeters," Radiation Protection Dosimetry, vol. 101, no. 1-4, pp. 515-518,2002
[42] C. P. a. B. Jacquier, "Fluorescence of Cu+ in NaCl single crystals," Journal of Physics C: Solid State Physics, vol. 13, no. 25, pp. 4791-4796,1980
[43] G. A. R.M. Bailey*, E.J. Rhodes, "OSL properties of NaCl relative to dating and dosimetry," Radiation Measurements vol. 32, no. 5-6, pp. 717-723,2000
[44] K. Liu et al., "Calibration and Statistical Performance of Al2O3: C Optically Stimulated Luminescent Dosimeters With and Without Annealing Using a 137Cs Source," Health Phys, vol. 116, no. 1, pp. 42-59,2019
[45] L. Waldner and C. Bernhardsson, "Physical and dosimetric properties of NaCl pellets made in-house for the use in prospective optically stimulated luminescence dosimetry applications," Radiation Measurements, vol. 119, pp. 52-57,2018
[46] P. A. Jursinic, "Optically stimulated luminescent dosimeters stable response to dose after repeated bleaching," Med Phys, vol. 47, no. 7, pp. 1-13,2020
[47] S. A. Abraham, S. J. Frank, and K. J. Kearfott, "An Efficient, Affordable Optically Stimulated Luminescent (OSL) Annealer," Health Phys, vol. 113, no. 1, pp. 2-12,2017
[48] L. A. Currie, "Limits for Qualitative Detection and Quantitative Determination," analytical chemistry, vol. 40, no. 3, pp. 586-592,1968
[49] L. A. Currie*, "Detection and quantifcation limits: origins and historical overview," Analytica Chimica Acta, vol. 391, no. 2, pp. 127-134,1999
[50] Y. Rodriguez-Lazcano, V. Correcher, and J. Garcia-Guinea, "Luminescence emission of natural NaCl," Radiation Physics and Chemistry, vol. 81, no. 2, pp. 126-130,2012